The Effects of Stanozolol on Body Weight of Sedentary Rats
Faculty Sponsor
This was not sponsored by a faculty, but Dr. Mike Sardinia supervised us and gave us guidance throughout the project.
Session Type
Poster Presentation
Research Project Abstract
Androgenic anabolic steroids (AAS) have grown in popularity over the years amongst competitive athletes, and it is common knowledge that many bodybuilders use them to supplement their muscle growth. Kicman (2003) suggests that AAS have the ability to change transcription factors that regulate hormone release – in this case, hormones that have masculinizing effects. Rats are commonly used when experimenting with AAS, and while there have been several studies done focusing on how AAS affect active rats’ muscle gains (Bocalini 2017; Tamaki 2009), little has been done to study whether idle rats’ gains are also noticeable. There also is a lack of research which use subcutaneous method of AAS injection. Most research uses intramuscular injection of AAS in order to study changes in body composition. This experiment attempted to determine if there would be idle rat muscle gain over a four-week period using 10 Sprague Dawley rats. Using Stanozolol in amounts based on the study done by Bocalini (2017), five of the rats were injected with the drug, while the other five served as the control and were given a sham injection. Rats were weighed once a week for a total of four weeks and the results were then recorded and trends analyzed. The rats injected with anabolic steroids gained an average of 27 grams of body weight, while the control group only gained an average of 10 grams, with a significant finding (p = 0.021),
Session Number
PS3
Location
HUB Multipurpose Room
Abstract Number
PS3-w
The Effects of Stanozolol on Body Weight of Sedentary Rats
HUB Multipurpose Room
Androgenic anabolic steroids (AAS) have grown in popularity over the years amongst competitive athletes, and it is common knowledge that many bodybuilders use them to supplement their muscle growth. Kicman (2003) suggests that AAS have the ability to change transcription factors that regulate hormone release – in this case, hormones that have masculinizing effects. Rats are commonly used when experimenting with AAS, and while there have been several studies done focusing on how AAS affect active rats’ muscle gains (Bocalini 2017; Tamaki 2009), little has been done to study whether idle rats’ gains are also noticeable. There also is a lack of research which use subcutaneous method of AAS injection. Most research uses intramuscular injection of AAS in order to study changes in body composition. This experiment attempted to determine if there would be idle rat muscle gain over a four-week period using 10 Sprague Dawley rats. Using Stanozolol in amounts based on the study done by Bocalini (2017), five of the rats were injected with the drug, while the other five served as the control and were given a sham injection. Rats were weighed once a week for a total of four weeks and the results were then recorded and trends analyzed. The rats injected with anabolic steroids gained an average of 27 grams of body weight, while the control group only gained an average of 10 grams, with a significant finding (p = 0.021),
