The Effects of Creatine Administration on Danio rerio Lean Muscle Mass and Oxygen Consumption

Research Project Abstract

Over the past decade, creatine has been speculated to have both beneficial and negative effects on human performance and training regimens. Known as an ergogenic aid, increasing creatine consumption within a diet has been understood to increase the total creatine and phosphocreatine levels of concentration found in muscles in humans. This supply of phosphocreatine and creatine allows for increased energy metabolism and increased exercise performance. Genetically similar to humans, zebrafish (Danio rerio) were separated into two groups: a control group that was fed a normal diet of fish food and an experimental group that was given the same fish food with an addition of creatine to supplement muscle growth. Over the course of the experiment, analyses showed no significant difference in oxygen consumption. However, statistically significant differences in lean body mass percentages were found between the creatine and control fish groups, supporting our hypothesis of creatine loading in zebrafish.

Session Number

PS1

Location

Graves Gym

Abstract Number

PS1-d

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Apr 23rd, 10:45 AM Apr 23rd, 12:15 PM

The Effects of Creatine Administration on Danio rerio Lean Muscle Mass and Oxygen Consumption

Graves Gym

Over the past decade, creatine has been speculated to have both beneficial and negative effects on human performance and training regimens. Known as an ergogenic aid, increasing creatine consumption within a diet has been understood to increase the total creatine and phosphocreatine levels of concentration found in muscles in humans. This supply of phosphocreatine and creatine allows for increased energy metabolism and increased exercise performance. Genetically similar to humans, zebrafish (Danio rerio) were separated into two groups: a control group that was fed a normal diet of fish food and an experimental group that was given the same fish food with an addition of creatine to supplement muscle growth. Over the course of the experiment, analyses showed no significant difference in oxygen consumption. However, statistically significant differences in lean body mass percentages were found between the creatine and control fish groups, supporting our hypothesis of creatine loading in zebrafish.